The Uploads Anti-Exploit Guard (UAEG) protects the WordPress uploads folder from being exploited with an .htaccess file that blocks remote access or execution of file types in your uploads folder that could be used to hack your website. It would depend on the file type. All file types that should NOT be allowed to be opened, accessed, processed or executed in your /uploads folder are protected by default. You can of course whitelist individual files or file types.
http://forum.ait-pro.com/forums/topic/uploads-anti-exploit-guard-uaeg-read-me-first/